Hugh Clarke

Biology of the Oocyte

List of Selected Publications

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Links

El-Hayek, S., Demeestere, I., Clarke, HJ. (2014). Follicle-stimulating hormone regulates expression and activity of epidermal growth factor receptor in the murine ovarian follicle. Proc. Nat. Acad. Sci. 111(47):16778-83.
Clarke, H. (2012). Post-transcriptional control of gene expression during mammalian oogenesis. Res. Probl. Cell Differ. 55, 1-21.
Mahrous, E. Q. Yang and H.J. Clarke (2012). Regulation of mitochondrial DNA accumulation during oocyte growth and meiotic maturation. Reproduction 144, 177-185.
Demeestere, I., A, Streiff, J. Suzuki, S. Al-Khabouri, E. Mahrous, S. L. Tan and H. J. Clarke. (2012). Follicle-stimulating hormone accelerates mouse oocyte development in vivo. Biol. Reprod. 87, 3, 1-11.
Bedard, N., Y. Yang, M. Gregory, D. G. Cyr, J. Suzuki, X. Yu, R.-C. Chian, L. Hermo, C. O’Flaherty, C. E. Smith, H. J. Clarke and S. S. Wing (2011). Mice lacking the USP2 deubiquitinating enzyme have severe male sub-fertility associated with defects in fertilization and sperm motility. Biol. Reprod. 85, 594-604.
Elizur, S.E., W. Y. Son, H. Clarke, D. Morris, Y. Gidoni, E. Demirtas and S. L. Tan (2011). A unique biological in-vivo model to evaluate follicular development during in-vitro maturation treatment. Reprod. Biomed. Online 22, 257-262.
Yang, Q., P. Allard, M. Huang, W-L. Zhang and H. J. Clarke (2010). Proteasomal activity is required to initiate and to sustain translational activation of messenger RNA encoding the stem-loop-binding protein during meiotic maturation in mice. Biol. Reprod. 82, 123-131.
Zhang, W-L., L. Poirier, M.M. Diaz, V. Bordignon and H.J. Clarke (2009). Maternally encoded stem-loop-binding protein is degraded in 2-cell mouse embryos by the co-ordinated activity of two separately regulated pathways. Dev. Biol. 328, 140-147.
Arnold, D.R., P. Françon, J. Zhang, K. Martin and H.J. Clarke (2008). Stem-loop binding protein expressed in growing oocytes is required for accumulation of mRNAs encoding histones H3 and H4 and for early embryonic development in the mouse. Dev. Biol. 313, 347-358.